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Molecular diagnostic techniques in healthcare are methods used to analyze and detect genetic and molecular changes in biological samples such as blood, tissues, and bodily fluids. These techniques are used to diagnose, monitor, and prognose diseases, as well as to predict an individual’s response to treatment.
Some examples of molecular diagnostic techniques used in healthcare include:
Polymerase chain reaction (PCR) - amplifies specific DNA sequences, making it possible to detect very small amounts of genetic material.
Hybridization - used to detect specific DNA or RNA sequences by binding them to a complementary probe.
Next-generation sequencing (NGS) - allows for the rapid and simultaneous sequencing of millions of DNA or RNA fragments, providing detailed information about the genetic makeup of a sample.
Real-time PCR - a PCR method that detects and quantifies the amount of amplified DNA as the reaction is occurring, it’s commonly used for viral load measurement.
Gene expression profiling - examines the levels of expression of many genes at once, and it is used to classify cancers and predict treatment response.
Molecular diagnostic techniques can be used to diagnose a wide range of diseases, including cancer, infectious diseases, genetic disorders, and inherited conditions. They are particularly useful in early disease detection and in identifying the presence of specific genetic mutations that may affect treatment decisions.
Overall, molecular diagnostic techniques play a crucial role in the healthcare industry by providing detailed information about the genetic makeup of a sample, helping to diagnose, monitor, and prognose diseases, and predicting an individual’s response to treatment.
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Diagnostic testing can play an important role in public health by stopping the dangerous squandering of effective medicines that are in short supply, says David Persing, chief medical and scientific …
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This advanced system uses continuous-flow centrifugation and optical detection technology, providing operators the ability to perform a wide variety of apheresis procedures on a single platform.
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Published Jan 1, 2022 Diagnostic Techniques and Procedures Molecular Diagnostic Techniques
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