Medical Subject Headings (MeSH): Genome-Wide Association Study

A genome-wide association study (GWAS) is a type of research study that looks for associations between genetic variations and certain health conditions. It involves analyzing the genetic information (genomes) of large groups of people to identify specific variations that may be associated with a particular disease or trait.

GWAS studies are typically conducted using large datasets, such as electronic health records or biobanks, and involve the analysis of hundreds of thousands or even millions of genetic markers. By comparing the genetic information of individuals with and without a particular health condition, researchers can identify specific variations that may be associated with an increased risk of the condition.

GWAS studies have been used to identify genetic associations with a wide range of health conditions, including cancer, cardiovascular disease, and psychiatric disorders. The results of GWAS studies can help researchers understand the genetic basis of these conditions and potentially lead to the development of new treatments or preventive measures.