Medical Subject Headings (MeSH): Renal Insufficiency, Chronic

Chronic renal insufficiency (CRI) is a condition in which the kidneys gradually lose their ability to function over time. It is also known as chronic kidney disease (CKD). Renal insufficiency means that the kidneys are not able to filter waste products from the blood as effectively as they should, leading to a buildup of toxins in the body.

The causes of CRI can be varied, but the most common causes are diabetes and high blood pressure. Other causes include glomerulonephritis, polycystic kidney disease, and chronic obstructive uropathy.

Symptoms of CRI can include fatigue, weakness, loss of appetite, nausea, vomiting, and weight loss. As the disease progresses, symptoms may become more severe and may include anemia, bone disease, electrolyte imbalances, and fluid buildup in the body.

In healthcare, the management of CRI typically involves controlling the underlying causes of the disease, such as managing diabetes and high blood pressure, as well as managing symptoms. Medications may be prescribed to control symptoms such as anemia and bone disease.

Dietary changes may also be recommended, such as limiting the intake of protein and phosphorus, in order to help slow the progression of the disease. In advanced stages, dialysis or kidney transplant may be necessary.

It is important to have regular check-ups with a primary care physician or nephrologist, who will monitor kidney function and the patient’s overall health, and make recommendations for treatment and lifestyle changes as needed.