On behalf of the Scientific Committee and the Center of Pharmaceutical Engineering I cordially invite scientists, researchers and professionals from industry, academia and research institutions to participate in the 5th International Symposium on Pharmaceutical Engineering Research – SPhERe. The conference will take place from October 18 – 20, 2023 in Braunschweig, Germany. SPhERe addresses major issues on innovative methods and processes to develop and manufacture effective and customized drugs in a cost-efficient manner. Bringing together pharmacists, process and production engineers as well as micro technologists from academia and industry, the conference will promote multidisciplinary exchange and collaboration. The symposium is an excellent forum specially for young scientists to share and discuss important new developments and scientific advancements in pharmaceutical engineering and related fields. In particular, we would like to motivate young professionals to exchange ideas with colleagues from Europe and beyond to present their results in this multidisciplinary setting. For early career scientists the conference offers the chance to get in touch with advanced researchers who will provide insight into their different career paths. The best posters will be honored with SPhERe Poster Awards.

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Highly potent active pharmaceutical ingredients, or HPAPIs, are potent compounds that could effectively treat serious and life-threatening diseases such as cancer. Because of their high potency, these substances eventually put the workers in the production facility at risk. While exceptional product quality is required, additional measures must be taken to ensure operator safety. At our online meeting, leading figures from the industry, occupational toxicologists and containment specialists will review the most recent developments affecting the handling of HPAPIs. The discussion will center on the safe and effective processing of potent APIs, process development and scale-up, occupational health hazards, toxicological assessment, improvements in isolators and facilities to minimize exposure risk, containment and cleaning validation practices, and risk management for cross-contamination. In the end, managing HPAPI safely and effectively necessitates a thorough evaluation of a number of factors. This September, keep a look out for any new developments in HPAPI production and processing.
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