Medical Subject Headings (MeSH): Mononegavirales

Mononegavirales is an order of viruses that includes several important pathogens that cause human diseases, such as:

Filoviridae family, which includes Ebola and Marburg viruses, both of which cause severe hemorrhagic fevers.

Rhabdoviridae family, which includes rabies virus, a fatal disease that affects the central nervous system.

Paramyxoviridae family, which includes measles virus, a highly contagious respiratory illness that can cause serious complications, particularly in young children.

Bornaviridae family, which includes Borna disease virus, a rare viral infection that can cause neurological symptoms.

These viruses are characterized by their negative-sense, single-stranded RNA genomes. The viruses of this order are known to cause a wide range of illnesses, from mild to severe and even fatal.

In healthcare, the detection and diagnosis of these viruses are important to prevent and control outbreaks. This requires a combination of surveillance, laboratory testing and contact tracing. Treatment of these viral infections is usually supportive, and in some cases, specific antiviral drugs or vaccines may be used.

It is also important to note that some of these viruses are considered as potential bioterrorism agents and public health officials are taking measures to ensure that they are not weaponized.