In a series of small retrospective and prospective studies, tumor feeding vessels were identified and selected. Using SIS, therapeutics were infused against vascular resistance, driving therapy into the liver tumor tissue while decreasing exposure to normal tissue.

Constructed for excellent pushability, the SIS supports accurate placement with improved levels of control. The ultra-thin, pliable and segmented construction, along with a hydrophilic coating, reduces friction for excellent tracking performance. The soft tip is tapered to offer easy access to the target.

Designed for dynamic movement, the SIS’ patented tip expands during infusion to support a pressure increase. Fluid dynamic modeling demonstrated that the SIS harnessed pressure from infusion to create flow within vasculature and overcame barriers to therapy delivery, as shown in a retrospective clinical study of therapeutic distribution in excised liver tumors.

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